The identities of the expected APAP metabolites were determined from accurate mass, isotopic fit, and fragmentation data obtained from SWATH acquisition and from comparison with standard compounds when available or spectra available in online libraries or the literature ( 11 )
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In the five in vitro studies, although a decrease in the apoptosis rate of granulosa cells was observed at specific doses, it was not confirmed whether this effect could translate into an improvement in oocyte quality in vivo (Fabov et al., 2023
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