The dual-pathway approach engages both the GHRH axis (upstream stimulation of GH synthesis and release) and the ghrelin axis (amplification of GH pulse amplitude) simultaneously, which published preclinical data suggests produces greater GH elevation than either compound alone
IGF-1 DES excels at localized, site-specific applications where researchers inject it directly into target muscles immediately before training
When expressed as a percentage increase in comparison to a placebo (1.31mIU/l or 0.4ng/ml), this augmentation appears to surpass 60-fold
High or frequent dosing is the main concern, and people with kidney, liver or other conditions are most at risk
Ramsey, M.M., et al., Functional Characterization of Des-IGF-1 Action at Excitatory Synapses in the CA1 Region of Rat Hippocampus
TESAMORELIN has been shown to significantly reduce visceral fat in patients with HIV-associated lipodystrophy, leading to improved body composition and metabolic health