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Some clinical experts and recent Phase 3 reporting have also noted that weight loss in some participants has been substantial enough to raise questions about how much weight loss may be too much, particularly when these medications are used outside tightly controlled medical settings and without provider supervision

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Patients taking Wegovy often report side effects, such as constipation, nausea, vomiting, heartburn, and diarrhea

The NLRP3 inflammasome is a cluster of proteins that triggers an inflammatory response and promotes the release of pro-inflammatory cytokines [27]