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The researchers found major aberrations in ROS clearance pathways, noting that Long COVID patients showed significantly lower levels of mitochondrial superoxide dismutase 2 (SOD2), a highly protective enzyme

If nausea persists beyond 3-4 weeks on a stable dose, consider reducing to the previous dose level and attempting re-escalation more gradually after 4-6 weeks

[6] One researcher summarized it bluntly: It is not possible to increase circulating glutathione to a clinically beneficial extent by the oral administration of a single dose of glutathione. [5] So why do people keep buying these supplements

In trials, 6-16% of participants discontinued due to GI adverse events

Nature (2007) 7