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Weeks 13 and beyond: 12mg weekly (maintenance)

Clinical trials, including SURPASS-2, have demonstrated significant improvements in HbA1c levels and substantial weight loss compared to other treatments, with effects becoming apparent within the first few weeks of treatment and continuing to improve over several months of consistent use

In research applications, KLOW is often examined for its role in aiding recovery of soft tissues such as muscles, ligaments, and skin

Statistical analysis We did not perform power calculations, but the sample size and animal number for each group were chosen based on study feasibility and prior knowledge of statistical power from previously published experiments