Redox Biol 14:3540 Zhu M, Zhang Y, Cooper S, Sikorski E, Rohwer J, Bowden GT (2004) Phase II enzyme inducer, sulforaphane, inhibits UVB-induced AP-1 activation in human keratinocytes by a novel mechanism
One study showed that regular use of aspirin actually slowed the progression of CKD in individuals over a 57 year period (Evans 2009)
Yes, the formula is vegan and cruelty-free
Its levels can be depleted, and replenishing them with standard supplements is less effective if your body isn't absorbing them well
Biochem Pharmacol 1985
Method Absorption Rate Advantages Disadvantages Oral pills 1.2-40% depending on intrinsic factor Convenient, widely available Poor absorption, especially with age or GI issues Sublingual Slightly better than pills No need for intrinsic factor, easy to use Still less effective than injectable forms In-clinic IM injection Nearly 100% Highly effective, professionally administered Requires clinic visits, potential travel and waiting time At home B12 injection Nearly 100% Highly effective, convenient, no travel needed Requires training, prescription, and comfort with self-injection IV infusion 100% Immediate delivery to bloodstream Most expensive, requires professional administration For many people especially those with serious deficiencies, digestive disorders, or pernicious anemia at home B12 injection offers the sweet spot of effectiveness and convenience