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Besides the brain glucose sensors, there are also glucose sensors located in peripheral tissues including the intestine [64], the carotid body [65] and mesenteric veins [66]

Safety profile and side effects The most frequently reported side effects were gastrointestinal symptoms, such as nausea, diarrhoea, and constipation

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The medication works by mimicking the action of the naturally occurring hormone GLP-1, which stimulates insulin secretion in a glucose-dependent manner, suppresses glucagon release, slows gastric emptying, and reduces appetite through effects on the central nervous system