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This specificity allows for the modulation of distinct neural circuits, offering highly selective therapeutic interventions (Dominguez-Paredes et al., 2021

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Human G1 and G2 were inserted into a pFastDual plasmid and were prepared by insertion of His 6 -tagged human G 1 fragment (BamHI/HindIII site) under the polh promoter and insertion of G 2 fragment (XhoI/SphI site) under the p10 promoter, respectively (Genewiz)

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