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At the level of gene transcription, the fact that three different proteins can be synthesized from gpx4, due to the presence of multiple transcriptional start sites, yielding the mitochondrial (m-), nuclear (n-), and cytosolic (c-) GPx4 forms, makes the issue of gene regulation extremely complex 54

10.1016/j.jaci.2005.08.059 25 ButtonB.CaiL

doi: 10.1016/j.freeradbiomed.2020.12.433 62

Barbatelli G, Murano I, Madsen L, Hao Q, Jimenez M, Kristiansen K, et al

Children 9(10):1494 Patelarou E et al (2012) Current evidence on the associations of breastfeeding, infant formula, and cows milk introduction with type 1 diabetes mellitus: a systematic review

In short, IGF-1 LR3 is like a cellular green light, nudging the body toward growth and repair