Provides Antioxidant Protection: Glutathione supports the skin by fighting free-radical damage, keeping it nourished and healthier in appearance
In the landmark 2017 study, FOXO4-DRI selectively induced apoptosis in senescent human fibroblasts (IMR90 cell line) while sparing non-senescent cells at an 11.73-fold selectivity ratio
doi: Ghrist A, Heil G, Stauffer G
This age-related reduction correlates with decreased tissue repair capacity and is hypothesised to contribute to age-related hair thinning and follicle miniaturisation
Appetite Regulation and Eating Behavior Research Satiety and Food Intake Studies Research on individual components revealed distinct but complementary appetite effects[17]: Cagrilintide reduced food intake through amylin-mediated satiety pathways in rodent models GLP3 decreased meal size and frequency through multiple receptor mechanisms Combined approaches showed additive effects on appetite suppression Food noise reduction reported anecdotally in human studies (reduced food preoccupation) Critical Research Limitation: While individual components (GLP3 and cagrilintide) have extensive phase 2 and phase 3 clinical trial data, research specifically examining the combined GLP3 + Cagrilintide formulation as a blend is extremely limited
In mice, fibroblast activity increased 3045%
