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In nematodes, transient diet scarcity blunts reproduction by inducing latency in germline stem cells, a reversible process which is undone once ambient nutritional factors improve [47, 48]

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The trial demonstrated a 20% reduction in the primary composite endpoint of cardiovascular death, nonfatal heart attack, or nonfatal stroke (hazard ratio 0.80, 95% CI 0.72-0.90)

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This results in better glycemic control, reduced appetite, and improved long-term glucose regulation