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The study found that CoQ10 monotherapy did not significantly reduce symptoms compared to a placebo, highlighting that a single nutrient may not be enough to overcome deeply entrenched mitochondrial dysfunction

Future developments may expand oral peptide options

20 Volunteers with metabolic syndrome were enrolled

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Ayad et al

Pro-caspase-1 is recruited to the complex upon inflammasome assembly and undergoes autoproteolytic cleavage to generate active caspase-1