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CCNs are assigned by CMS and used to identify healthcare facilities participating in the Medicare Part A and Medicaid programs

For GHK-Cu specifically, the logic is sound even without direct evidence: cumulative copper exposure is lower with reduced frequency, and the gene expression changes initiated during loading persist during maintenance

Rascle A, Johnston JA, Amati B

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You can look at Table 2 in the paper yourself

Hepatocyte growth factor improves functional recovery by attenuating endoplasmic reticulum stress-induced apoptosis in peripheral nerve injury