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[16] [17] Healthcare professionals should provide clear written and verbal instructions on site rotation during treatment initiation and reinforce these principles at follow-up appointments

However, further studies are needed to investigate the success of uORF targeting in disease models as many of these studies have been proof of principle rather than demonstrating success in disease models

*Correspondence: Qilai Huang, [email protected] These authors contributed equally to this work This article was submitted to Cellular Biochemistry, a section of the journal Frontiers in Molecular Biosciences Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

The most commonly reported side effects were mild to moderate gastrointestinal issues, such as nausea, vomiting, diarrhoea, and constipation, which tended to occur during the higher dose period

It works as a glucagon-like peptide-1 receptor agonist and is primarily used to treat type 2 diabetes

Many studies lack control groups, meaning we cant distinguish peptide effects from placebo effects or natural healing