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Efficacy, safety and tolerability of oral semaglutide versus placebo added to insulin metformin in patients with type 2 diabetes: the PIONEER 8 trial

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Fibroblast activation and ECM remodeling Biomolecules (2018) Anti-Inflammatory Inflammation Modulation Bioinformatic analyses show GHK-Cu downregulates gene networks associated with inflammation and oxidative stress, potentially explaining its tissue repair properties

Benchmarking against SUSTAIN-6 and SURPASS-CVOT In the emulation of SUSTAIN-6 comparing semaglutide to sitagliptin, a proxy for placebo, in patients at moderate and high cardiovascular risk (Table 2 and Supplementary Table 19), the hazard ratio (HR) for the primary endpoint was 0.68 (95% confidence interval (CI) 0.600.77) compared to the trial estimate of HR 0.74 (95% CI 0.58 to 0.95)

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