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This dual action, building while reducing breakdown, shifts the collagen balance decisively toward net accumulation

The hallmark features of AD include the accumulation of amyloid-beta (A) and the formation of neurofibrillary tangles in the brain 1

Notably, anthocyanin biosynthesis is believed to occur on the surface of the endoplasmatic reticulum in membrane-associated enzyme complexes, so-called metabolons 46

In general, B-vitamins have small body pools at a cellular level and due to their fast turnover, deficiency can be developed rapidly under conditions of restricted dietary intake

4 Patients may also have some GI upset with nausea, vomiting, or diarrhea

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