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Protein analysis of biopsy samples Muscle biopsy samples were allocated for protein determination by western blot analysis with antibodies (New England BioLabs, Mississauga, ON, Canada) against total and the phosphorylated protein targets: mTOR, phospho-mTOR (Ser2448), p70-S6K, phospho-p70-S6K (Thr389), 4E-BP1, and phospho-4E-BP1- (Thr37/46)

utilized a clustered regularly interspaced short palindromic repeat (CRISPR) screen, which identified AARS1 as an intracellular sensor for lactate and a transferase of lactyl to lysine residues

751 obese adults without diabetes were randomized to maximum tolerated doses of tirzepatide versus semaglutide over 72 weeks

If youre thinking about stopping semaglutide, talk to your doctor first