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doi: 10.1038/s41586-019-1836-5 193 KurtulusSMadiAEscobarGKlapholzMNymanJChristianEet al

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[55] This biochemical cascade increases mitochondrial thermogenesis, effectively forcing the body to dissipate excess calories as heat and increasing overall energy expenditure

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No single mutation in fbf-1 or fbf-2 was identified in genetic screens designed to identify mutants phenocopying fbf RNAi (Zhang et al., 1997), supporting the idea the fbf-1 and fbf-2 function redundantly to regulate sex determination within the GSCs