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Connolly HM, Crary JL, McGoon MD, Hensrud DD, Edwards BS, Edwards WD, et al

Upon activation by toll-like receptor 4 (TLR4) and the receptor for advanced glycation end products (RAGE), macrophages initiate the synthesis of interleukin-6 (IL-6), tumor necrosis factor-alpha (TNF-), and other inflammatory biomarkers, resulting in further hepatic injury (Guilliams and Scott 2022)

The Core Question: How Much BPC-157 Orally

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The subcutaneous tissue adjacent to the injury provides an optimal depot from which BPC-157 diffuses to target structures