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In some nerve conditions, such as CIDP, certain antibodies (IgG) can also contribute to nerve inflammation

In addition, dsDNA-induced cGAS-STING signaling has been shown to promote the development of arthritis through the induction of inflammatory factors in FLSs, accompanied by enhanced migration and invasion (63, 65)

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However, DPP-4 inhibitors have not reduced the risk of major adverse cardiovascular events, possibly because potentiation of SDF-1 enhances plaque growth and instability, activates deleterious neurohormonal mechanisms, and promotes cardiac inflammation and fibrosis

doi: 10.1038/s41467-024-49133-z 370 WangR.LanC.BenlaghaK.CamaraN