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By targeting both arms of the vicious cycleSirt1/Nrf2/HO-1/GPX4 for ferroptosis and TLR4/NF-B for inflammationEDV exemplifies a cycle-disrupting therapeutic strategy
Molecule 20:1768417719 Ni WJ, Ding HH, Zhou H, Qiu YY, Tang LQ (2015) Renoprotective effects of berberine through regulation of the MMPs/TIMPs system in streptozocin induced diabetic nephropathy in rats
it helps move the nutrient across the final "gate" and into the cell where it can do its work
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