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Further, treatment with Lactobacillus acidophilus can reduce the increased intestinal permeability caused by stress in rats ( Streptococcus , Prevotella , and Lactobacillus in PPI-treated patients suggests that these strains may also be involved in PPI-induced FD

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For most patients, these early effects come and go and improve as the body adapts especially when treatment starts at a low dose and increases gradually

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Unlike many supplements, it has demonstrated direct effects on the GI tract , including accelerated healing of ulcers, improved intestinal barrier integrity, and protection against NSAID damage