Beyond its central role in apoptotic regulation, the tumor suppressor protein 53 (p53) critically contributes to ferroptosis by suppressing SLC7A11 expression
Glutathione is the master antioxidant to quench the reactive oxygen species produced as byproducts, allowing ATP production without the damaging impact that can occur in an environment lacking adequate antioxidant capacity
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This helps to detach B12 from the proteins that it is originally attached to
Glutathione pool and enzymatic antioxidant activities When exposed to oxidative stress, plants can activate their oxygen scavenging systems by increasing the activity of antioxidant enzymes or by mobilization of their non-enzymatic antioxidants, such as reduced glutathione (GSH) 42,55