Circulation 137:14501459 UK Prospective Diabetes Study (UKPDS) Group (1998) Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33)
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Research surrounding this acetylated derivative of L-carnitine has demonstrated that the acetyl group can serve as a metabolic building block for acetylcholine, a brain neurotransmitter, while the L-carnitine component carries fatty acids into mitochondria of nerve, heart, and muscle cells for use in energy production.In addition, it may benefit membrane stability, production of nerve growth factor, and cerebral blood flow.
Preserved incretin activity of glucagon-like peptide 1[7-36 amide] but not of synthetic human gastric inhibitory polypeptide in patients with type-2 diabetes mellitus