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Major cardiovascular outcome trials, including LEADER, SUSTAIN-6, and REWIND, followed patients for several years

However, GLP-1 RAs significantly increased the change in the 6-min walk test (MWT) distance (MD: 19.74, p = 0.002)

But it can also reduce your risk of these conditions if youre high-risk, including people with diabetes. GLP-1s and Metformin Are Most Beneficial When Combined Diabetes is a complex health condition, explains King

This matters most during dose increases, when providers are trying to decide whether your body is adjusting well or reacting poorly

Our previous studies have demonstrated that sitagliptin may protect diabetic fatty liver by reducing ROS production and NF-B signaling pathway activation [106]

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