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( 10.1093/humrep/dew284) [DOI] [PMC free article] [PubMed] [Google Scholar] Reuter SE, Evans AM.2012

Phase 2b data show berobenatide conferred robust weight loss and tolerability across different doses and intervals

Whether the hyperprolactinemia, amenorrhea, and galactorrhea were secondary to the hypothyroidism or were independent problems was at first unclear

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After discontinuation, close monitoring is essential: weight should be checked every 4-8 weeks initially, and for diabetes patients, self-monitoring of blood glucose or continuous glucose monitoring should continue as indicated, with A1C assessment within approximately 3 months of stopping to detect metabolic deterioration early and implement alternative management strategies