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In senescent cells, FOXO4 binds and sequesters p53, preventing it from triggering apoptosisthis is how damaged cells survive despite accumulating stress

7 common vitamin and mineral deficiencies that impact metabolic health Vitamin and mineral deficiencies are less common in the United States and developed countries than in countries lacking access to safe, quality food and healthcare---but they're still surprisingly prevalent

Cellular glutathione plays a major role in the defence against redox cycling-derived oxidative stress, either by direct interaction with ROS, RNS and electrophiles, or by acting as a co-factor for various enzymes 11,12

With this flurry of activity, were probably going to see some very exciting new medicines that could be even better than the ones we have now.

N Engl J Med 379:226235 McGann PT, Ware RE (2015) Hydroxyurea therapy for sickle cell anemia