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This clean safety profile contributed to the FDA granting GRAS (Generally Recognized As Safe) status for AOD-9604 as a food ingredient in 2007

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PubMed 22962027 TB-4 Phase 1 human safety first-in-human randomized, double-blind, single- and multiple-dose Phase 1 of recombinant human thymosin 4 in healthy volunteers, no serious adverse events: PubMed 34346165

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Tyrosine phosphatase Shp2 accelerated the progression of dilated cardiomyopathy via upregulating NF-B/Src/FAK signaling induced ROS and mitophagy

Frykns, M