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Hydroxocobalamin, in particular, is retained in the body longer than cyanocobalamin, which can reduce the frequency of repeat injections

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Rarely, the medications may cause thyroid cancer among high-risk patients

These findings are complemented by neuropathological evidence from postmortem studies, where chronic alcoholics show reduced density of serotonin (5-HT) transporters in the raphe nuclei and diminished hippocampal neurogenesis, paralleling changes seen in depressed individuals without AUD (Pierson et al

( g ) HTML:TML ratio was assessed in FT282-CCNE1 cells treated with the IDH1 inhibitor and supplemented with KG (n = 8 technical replicates representative from 2 independent experiments)

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