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Elevated UA levels promote a pro-oxidative and pro-inflammatory state with both conditions playing a crucial role in the pathophysiology and development of CVD

Despite the prevalent use of synthetic drugs in the standard treatment of rheumatoid arthritis, the therapeutic journey is often marred by side effects

Homocysteine and low folate promote chronic inflammation and autoimmunity (by reducing Tregs and increasing Th17 cells)

Through upregulating TP53 activity, GNA lowered the expression levels of GPX4 and SLC7A11, leading to dysregulation of cellular lipid peroxides, and eventually ferroptosis in transforming growth factor-1 (TGF-1)-induced EMT melanoma models (Wang et al., 2020)

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oleifera , four compounds were isolated