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Practically inadvisable

This is particularly important for patients suffering from severe spinal cord injuries, where conventional treatments often offer limited benefits

Reconstituted solution is more vulnerable because hydrolysis, contamination risk, temperature swings, and repeated vial access all become more important

Limitations and Research Status While preclinical data is extensive, large-scale human clinical trials are limited

B12 shots for malabsorption or dietary restriction Vegans, vegetarians, older adults, and people with GI conditions (Crohn's disease, celiac disease, pernicious anemia) commonly have inadequate B12 absorption

A separate 2025 rat study showed that oral BPC-157 at doses of 10 mcg/kg per day promoted muscle-to-bone reattachment after surgical detachment