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Factors such as trauma, nutritional deficiencies, irritable bowel disorders, leaky gut, microbiome dysbiosis, and immune dysregulation can all contribute to the generation of ROS, leading to tissue damage and ulcer formation

This purification protocol allows a more efficient use of monomeric Fabs compared to Driscoll et al., which requires a 5-fold Fab excess in the second coupling step 34

Peptide bonds are cleaved by proteolytic enzymes in the GI tract within minutes of ingestion