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Other situations requiring prompt medical contact include signs of allergic reactions (difficulty breathing, swelling of the face or throat, severe rash)call 911 for severe allergic reactionssymptoms of thyroid tumors (a lump or swelling in the neck, hoarseness, difficulty swallowing), or signs of kidney problems (decreased urination, swelling in legs or feet, unusual fatigue)

Sequence-specific primer pairs are shown in Table S1

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doi: 10.1056/NEJMoa1503747 160 TamadaSIguchiTKatoMAsakawaJKitaKYasudaSet al

When the melanocyte cells (your hair's color producers) slow down or stop making pigment, you get gray or white hair