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To reduce these potential risks, healthcare providers are advised to closely monitor patients, particularly those with a history of gallbladder or biliary disease [49]

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8 Concerningly, lifestyle improvements are often difficult to sustain, underscoring the potential benefits of early initiation and background therapy with GLP-1RA due to its benefits on metabolic disorders (Table 3) and chronic liver disease

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Of these, the role of BDNF has generated interest among nutritionists because it has been suggested that some food components (e.g., docosahexaenoic acid and curcumin) may act as neuroprotectants by affecting the levels of this neurotrophin in the brain (Wu et al., 2004

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doi: 10.1002/mds.10486

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