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TGF- interacts with type I (TGF-RI, often referred to as ALK5) and type II (TGF-RII) receptors, promoting the phosphorylation of SMAD2 and SMAD3

Instead of mimicking 1 hormone, tirzepatide mimics 2 hormones, which is thought to enhance appetite suppression

This narrative review aims to explore the intricate molecular mechanisms underlying ethanol-induced depression, synthesizing findings from preclinical and clinical studies

10.1002/clc.4960190713 137 KroumpouzosG.TraversR.AllanA

References Devarbhavi H, Asrani SK, Arab JP, Nartey YA, Pose E, Kamath PS

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