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This slightly gentler absorption curve from the thigh may actually explain the lower nausea rate found in clinical research

Safety and effectiveness in pediatric patients have not been established

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Typical daily intake targets are about 600 IU per day for most adults, and 800 IU per day after age 70

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We scoured the medical database looking for reactions to any form of B12, and all we could find were ten cases (which all happened in reaction to either cyano or hydroxy B12, not the other forms)