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At the same time, we purified tdTomato-negative striatal cells (which include any other cell type in the striatal tissue) from both controls and mutants (here called iSPN wt and iSPN mut, respectively)

First, the COA should name the actual lab (not "an independent US lab")

Matrix metalloproteinases (MMPs) are enzymes responsible for the catalytic degradation of protein (extracellular matrix)

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It ensures that any possible issues are identified early and dealt with quickly