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doi: 10.3389/fncel.2020.00198 75 KraftA

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In addition, Researchers found that Rut can also regulate the level of glutamate, reduce the expression of glutaminase and NMDA receptor subunit glun2b, and increase the expression of excitatory amino acid transporter (EAAT), glutamine synthetase (GS) and AMPA receptor subunit GluA1 and GluA2 ( Rut can also inhibit activated astrocytes, downregulate inflammatory molecules such as interleukin-1 (IL-1), interleukin-6 (IL-6), tumor necrosis factor- (TNF-), high mobility group protein B1 (HMGB1), interleukin-1 receptor 1 (IL-1r1) and toll like receptor 4 (TLR-4), and upregulate the protein expression of anti-inflammatory molecule interleukin-10 (IL-10)

2014;9(11):e112737

Sastoji se od tri aminokiseline-cisteina, glutaminske kiseline i glicina