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Similar to the immunohistological studies, microarray analysis showed that inhibition of the proteasome may have both neuroprotective and pro-apoptotic response in primary neuron cells through upregulation of neuroprotective heat-shock proteins (HSPs

76 , 24452450 (2010) DOnofrio, A

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For instance, during periods of increased stress or illness, the demand for glutathione rises, underscoring its importance in immune response

doi: 10.1016/j.pharmthera.2013.09.006 235 RyuG.ShinH.-W

Short-term KD interventions have demonstrated an increase in fibroblast growth factor 21 (FGF21) levels and a reduction in interleukin (IL)1 secretion by macrophages [99]