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Esta propriedade est diretamente relacionada sua origem gstrica: ele resiste degradao enzimtica no estmago, o que abre caminho para uma administrao oral uma vantagem considervel em comparao com outros peptdeos que necessitam obrigatoriamente de injeo

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The structure shows that important hydrophobic ligand-receptor interactions are conserved in agonist- and antagonist-bound forms of the extracellular domain, but certain residues in the ligand-binding site adopt a GLP-1-specific conformation

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In these cases, the slowed gastric emptying caused by your weight loss medication is not a factor