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After roughly 18 months, the average participant who got 10 or 15 milligrams of tirzepatide per week lost roughly 20 percent of their initial weight

doi: 10.1007/s00281-017-0619-z 56 CroftMSiegelRM

Understanding Covid-19 [Preprint] Villarreal-Caldern JR et al (2019) Interplay between the adaptive immune system and insulin resistance in weight loss induced by bariatric surgery

doi: 10.1177/1934578X1501000142 28 RevelouP

Food and Drug Administration (FDA) does not review non-drug health products (e.g., herbals, nutraceuticals, shampoos, and other supplements) for safety or effectiveness before they are sold to the public

And so doctors are increasingly prescribing the drug off-label, purely for its effect helping people lose weight