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The absence of a boxed warning on cagrilintide reflects the absence of an approved label not a demonstration that it is safer

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This adaptive slowdown makes long-term weight maintenance increasingly difficult and helps explain why weight regain is so common once medication support is reduced or stopped

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GLP-1 is involved in glucose homeostasis, and activation of GLP-1R in the plasma membrane of pancreatic beta-cells potentiates glucose-dependent insulin secretion