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Renal-sparing modifications, such as 68 Ga/ 177 Lu-DOTA-Lys40-exendin-4, have been shown to reduce renal radiation exposure by up to 60% while maintaining high tumor affinity, thereby supporting their advancement into early-phase human dosimetry trials [348, 444, 445]

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Abbreviations ACTH: Adrenocorticotropic hormone CML: Chronic myeloid leukaemia MITF: Microphthalmia transcription factor References Hassona Y, Sawair F, Al-Karadsheh O, Scully C (2016) Prevalence and clinical features of pigmented oral lesions