Another great thing about Immunocal is that it has helped me avoid sickness
Methylene blue is theorized to provide hemodynamic support by combating the nitric oxide (NO) induced vasodilation in amlodipine overdose by acting as a NO scavenger, preventing NO production, and impeding cGMP production.[20] While there have been reports of hemodynamic improvements in those with refractory shock, the overall evidence behind its benefit is sparse.[20,22,3,5] Other treatments that have been described but not well studied included sodium bicarbonate infusion (thought to work by correcting the acidosis that enhances calcium channel blocker binding to L-type calcium channels), phosphodiesterase III inhibitors, levosimendan, L-carnitine, and mechanical support with an intra-aortic balloon pump.[5,23] Overall, these modalities are not recommended as the evidence supporting them is lacking, but they can be considered as a last resort in those not responding to the therapies previously described above
A 2011 study in The Journal of Physiology even found that long-term L-Carnitine supplementation improved muscle carnitine content and fat metabolism during moderate exercise
Galluzzi L, Vitale I, Aaronson SA, et al
Drug Alcohol Dependence
However, it is worth noting that in the research conducted by Daniluk et al
.png)
