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With those data in hand, my colleagues and I started trying to interpret it

The increased endothelial cell permeability is generated by TGF1 via SMAD3-dependent signaling, which upregulates matrix metalloproteinase-9 and downregulates claudin-5

During this period, the neurons already receive synaptic inputs from neighboring cells (Petreanu and Alvarez-Buylla, 2002)

When GA is administered, AMPK is phosphorylated, and acetyl-CoA carboxylase 1 (ACC1) and ACC2 are both inactivated by AMPK, therefore inhibiting the conversion of acetyl-CoA to malonyl-CoA, thus blocking fat synthesis (J et al., 2023)

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