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Studies with mutants and transgenic plants over- or under-expressing enzymes or metabolites of the AsA-GSH pathway have proved very well the co-relation between this pathway and stress tolerance (Gill and Tuteja, Each enzyme of the AsA-GSH pathway has various subcellular isoforms, which differ from each other with respect to their spatial and temporal expression
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*Correspondence: Hongjun Li, [email protected] These authors have contributed equally to this work Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
This opens up a new area in which a non-traditional target may be employed to inhibit protein turnover, although how this type of inhibitor could achieve specificity is not clear at present
Antioxidant The antioxidant function of GSH mainly relies on enzymatic pathways involved in cellular defense against reactive oxygen species (ROS)
Diabetic ketoacidosis should be treated with insulin [see Warnings and Precautions (5.1) and Warnings and Precautions (5.2)]
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