Conclusion BBB-targeted polypeptide nanoparticles coupled to therapeutic molecules were effectively taken up by brain organoids or showing a BBB protective effect indicating potential applications in nervous system pathologies
Yu W, Liu W, Xie D, Wang Q, Xu C, Zhao H et al (2022) High level of uric acid promotes atherosclerosis by targeting NRF2-mediated autophagy dysfunction and ferroptosis
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As a rule, projection neurons with long axons are more vulnerable than local circuit and projection neurons with short axons, which tend to be spared
although the compounds are natural, they are not known to exist in nature and are derived from another protein (Bdis et al