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10.1111/j.0954-6820.1968.tb02452.x [DOI] [PubMed] 51.Chapman LE, Darling AL, Brown JE (2016) Association between metformin and vitamin B12 deficiency in patients with type 2 diabetes: a systematic review and meta-analysis

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Symptoms of a serious allergic reaction may include: swelling of your face, lips, tongue, or throat, fainting or feeling dizzy, very rapid heartbeat, problems breathing or swallowing, and severe rash or itching Talk with your health care provider if you are not sure if you are pregnant or planning to become pregnant