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A prior episode of acute pancreatitis on semaglutide should prompt a careful risk-benefit discussion before switching to tirzepatide rather than a straightforward transition

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At the molecular level, semaglutide has both pro-thrombotic effects (primarily through dehydration, muscle loss, and B12 depletion) and anti-thrombotic effects (through direct platelet inhibition, nitric oxide enhancement, anti-inflammatory pathways, and PAI-1 modulation)

A lower body lift addresses the abdomen, outer thighs, buttocks, and lower back in a single circumferential operation