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2 Institute (College) of Integrative Medicine, Dalian Medical University, Dalian, Liaoning, 116044, Peoples Republic of China

If you have a vitamin B12 deficiencyperhaps due to conditions like pernicious anemia, certain digestive disorders, or a strict vegan dietyou may experience symptoms such as fatigue, weakness, and low energy

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IGF-1 is the primary marker monitored

Oxidative stress worsens mitochondrial damage The elevated production of ROS has been shown to induce depolarization of the mitochondrial membrane potential (m) and the subsequent opening of the mitochondrial permeability transition pore (mPTP) [76, 77]

Balbas GM, Regana MS, Millet PU